proper desktop
The number one tweak is the script this guy wrote:
http://www.aspireoneuser.com/forum/viewtopic.php?f=31&t=1256&st=0&sk=t&sd=a&hilit=desktop+script
Basically strips off the custom front end on Linpus and gives you a proper desktop + updates a whole bunch of stuff and it really does run as simply as he says.
Next I'll be looking into some of the custom fan speed control scripts people are working on.