Arthur C. Clarke quote
"Two possibilities exist: either we are alone in the Universe or we are not. Both are equally terrifying." ®
I don't think so. There can be thousands of technologically advanced civilisations in the rest of the universe and it would make no difference to us whatsoever. All the tests we've done so far have supported Einstein's theories (the latest from Ars: https://arstechnica.co.uk/science/2017/06/einstein-still-annoyingly-right-as-researchers-weigh-white-dwarf/) so the speed of light is still the limit.
That means realistically, our chances of communicating with any civilisation more than a hundred light years away is pretty much zero. And space is way bigger than that*. Even if we only consider our own galaxy, there's room for dozens of civilisations like us, all of which are too far away for us to talk to in any meaningful time frame. So not so terrifying after all.
*Douglas Adams quote goes here.