Re: "but could for example, also be done through ads on a trusted website"
I'll add the ever famous Pi-Hole to the list, as well as stop social, ghostery and NoRef for your browsing pleasure.
I was really put off the other day when I visited a website, by a knowledgable IT guy now has some shitty overlay on his website that complains about your adblockers, and wants you to click on an ad to get access to his site, which is really sad, as his mojo saved me hours of mindless searching. I get it that he needs to keep his site running and that cost money. Unfortunately, ad slingers could care less about your computer security, and I won't take the chance.