Re: no one has been able to invent new pronouns that sound natural as drop-in replacements
OK - you have a good idea.
Let's INVENT SOME PRONOUNS!
I suppose El Reg commenters might have some really good suggestions.
In the mean time we could just use 'semprini' for all non-sex-specific cases...
(most o the things I'm thinking of are profane and have more than one syllable, with a profane term followed by 'face' 'head' 'brain' or has 'ass in it somewhere')