Well now....
They make extra-large Depends, but the intended use is for people who are incontinent. After a 48-hour gaming session, they probably need a crane to pick their ass off the chair will a full diaper because they were too lazy to unload their ammo into the loo. Seriously though, that is taking the game too far. I have heard of things like this when I was playing World of Warcraft, like people being found dead in front of their computers because they were chugging energy drinks and their kidneys failed.