We are talking about deliveries to residential areas extending into the evening hours.
Deliveries between commercial operations, usually in zones designated for business activities, during business hours would not be an issue. After all, organ deliveries are already often done by helicopter, significantly louder than drones. And other deliveries to business are frequently done by large trucks, such as semis, again likely louder than these home delivery drones.
So, until we can regularly do organ transplants in the home, I can't think of anything that doesn't require professional assistance (i.e. a medical practioner or the like) that would require such high-priority deliveries to residential addresses that a car/van/motorcycle/bicycle delivery system wouldn't be adequate.