Once you bring in other people, you have people who when informed by the authorities of how many years they face in the slammer, will turn.
Best not to operate in a jurisdiction where you stand to get life without parole, or one that will extradite you to same. Good luck finding one.
And NEVER be in proximity of evidence. That's a tough one.
There's been a few Silk Road successors. Some have been caught. Others have suddenly folded their tents and absconded - perhaps the best strategy as you can be gone before the investigators can track you down.