I thought I wouldn't comment on this post, as the topic is really enterprise oriented and I'm just a home user with variously 12 or 15 drives installed in or connected to variously 6 or 7 PC's and notebooks in a home network. But I see other small-time users commenting below, so I felt I had to jump in.
Everything I have is always running 24/7.
Everything I have that came with a hard drive, I immediately replaced the drive with a higher capacity Seagate drive. Always. 1 or 2 TB 2 1/2 inchers in the notebooks, and 2 or 4 TB 3 1/2 inchers in the desktops. I guess I standardized on Seagate years ago because of the free DiskWizard cloning thing they provide. DiskWizard has been totally bulletproof for me for cloning. Never a hiccup.
I have never had an ounce or a blip or a jot or tittle of trouble with a Seagate drive--ever. My AFR has been zero. Even if I had one go tits-up and screech itself to death tomorrow, I would still be high on Seagate. (Maybe the next one, not so much...) It does, in fact, surprise me that these unbelievably complicated $100 products work so well.
The reason I felt compelled to make this hearty endorsement here (I don't work for Seagate, etc. etc.) is that it seems to me that bellyachers and bad-mouthers are often the main people that ever post anything. Some people love to boast that, in their huge profound experience, a wide-spread, huge volume, successful product like a Seagate drive is crap. An AFR in the 1% range, to me, for something like an HDD, either absolutely or relative to competitors, is totally fine with me. If the price is right, I'll keep buying, even as an enterprise user. IT'S THE ENTIRE REASON FOR A SOLID BACKUP REGIME. To call Seagate drives "crap" or "shit" (same thing) is fairly unintelligent. Huh ?