No hassle here.
Company with over 1000 employees, and use MobileIron platform, and insist on Android (not iOS), and rollout has been painless and works really well. As our entire platform is Android (as most of the world is Android), we don't have any app compatibility headaches, and we can lock out really old Android devices that aren't patched to at least a reasonable level. No security issues, no app issues, no support issues, it just works, and saved us massive amounts of resources/money/frustration/training that we used to suffer. Users are happy, management are happy, IT are happy.