"VMWare ESX and NSX etc."
This isn't the cutting edge. AWS, Google Cloud, etc are the cutting edge. Does any enterprise, tradition enterprise, have anything that can run like, for instance, Google search? Index a few trillion records and provide a few hundred million results nearly instantaneously and do that for a billion users at the same time... never down or slow or inconsistent regardless of location, connection, device... if a few hundred million users decide to unexpectedly jump on the application, no big deal.