@AC - Skylon's something I'm really hoping gets built this time, and teh chances aren;t looking too bad at teh moment with Reaction Engiones actually getting some backing and interest at the moment. But it'll be best at high-frequency low tonnage to LEO scenarios compared to the 'glorified fireworks' that can carry much heavier payloads.
Skylon is a part of what we need for an integrated space transport system (and it'd certainly make getting into orbit a damned sight comfier due to lower G-forces involved such that a large percentage of the population could potentially travel into space, compared with current techniology), but we need the 'glorified fireworks' too, to do the heavy lifting and the interplanetary stuff.
We also need an orbit-to-orbit shuttle (ie: always in space, never lands),/space tug too. It'll come.