The US market is a little different to other countries. It's heavily city based, and one city responds differently to another. Compare San Francisco to Princeton, Texas, for example. Or even Ann Arbor to Detroit.
There is a much stronger argument for regional marketing in the US than in the UK. We have regional differences but they are less significant and the borders are much softer. The only real US style boundary we have is the Severn and even that doesn't stop people commuting to Cribs Causeway.