Can't be a single movie
There is far too much content in the book to make a single 2 or 3 hour movie. Even the 3 part mini-series left out a lot of details. Now, if they could do something similar to LOTR with 3 or 4 movies...
Not sure how well the movie would be received these days though considering Paul leads a series of terrorist attacks against the local government to finally take power from the Emperor.