Re: Well
The brain is not just a collection of neurons and memories. Its layer upon layer of filters and simulators built from experience but also built on the ready built in models from our genes and whatever goes on in the womb.
It would be like trying to run an ARM binary on an Intel PC.
I had a friend who lost a leg and 30 years later would still sometimes get out of bed and fall over. Imagine what it would be like waking up in something that was just slightly wrong everywhere.