Rotated screens and "pranks"
The interesting thing about rotated screens that they are perfectly fine when viewed using remote control software. So when the "Georges" on the service desk keep passing these calls through, I just remote in and open up the Intel system tray thingy set the screen the right way up and disable the hotkeys bit.
I have seen some of those pranks in the field - the screenshot,set as wallpaper, hide icons. All the user did was call IT to sort it while he went to lunch (think it was logged as "Mouse button not working"
The other bloody joker had changed the desktop to the default Windows XP desktop that had a "Windows is formatting c:" dialogue box superimposed.
What do the victim do? Panic, switch off the PC and call IT, demanding high priority call to resolve it. Fair enough, it was in the A&E department of a largish hospital after all. Was very close to putting in an official complaint.