Reply to post: Re: I'm buggered

Coffee fixes the damage booze did to your liver, study finds

Michael Wojcik Silver badge

Re: I'm buggered

Coffee enema?

That seems dangerous. Someone could absorb quite a lot of caffeine very quickly that way, depending on the volume of coffee involved. I suppose many people would just get a buzz from the resulting adrenaline surge,1 but it seems like for many it could also produce the usual adrenaline side effects, like hyperventilation and heart palpitations, and possibly more serious events.

Also, it seems like rather a waste of good coffee.

1AIUI, caffeine, quite a small molecule, crosses the blood-brain barrier and binds to adenosine receptors in the brain. That both blocks the calming effects of adenosine and causes the brain to stimulate the adrenal glands. But I'm no endocrinologist, so someone may correct me on that point.

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