Re: graeme@the-leggetts.org.uk
"Plus also it takes a fairly massive dose of it to do any sort of damage"
The LD50 of paracetamol is 200% of the effective dose - where the effective dose for the average 60-90kg human is roughly 1000mg 4 times in a day. This is one of the closest margins between effective and Uh Oh for any painkiller and the closest for any OTC one.
As a pharmacist and doctor both pointed out to me, paracetamol is one of those analgesics where taking less than the effective code means you may as well not bother (I get stinking migraines which only respond to a cocktail of analgesics and only if caught early. if not, you lose a day with blinding headaches and throwing up or worse)
Biting the hand that feeds IT
