Last year I was sitting on a plane preparing for take-off. We were informed that the co-pilot's microphone wasn't working. After 10 minutes, the solution was to power cycle the aircraft. 15 minutes later we were on our way.
Not as frustrating as the previous incident where the pilot's window wouldn't open. Apparently it is their emergency exit and we couldn't take off with it stuck. After an hour of banging coming from the front, we transferred to another plane. I didn't feel as bad as the person next to me who watched the flight she was originally booked on depart.