Re: Personally ...
Why so? For simple things (text, the occasional title, table or image, regardless of length) rst markup is enough (usually I just rst2pdf it). For more complex stuff I use lout. Never a problem with putting half a word in italics or with randomly-shifting left alignments etc. That alone makes it worth trying... not to mention, the result is beautifully typeset.
For collaborative work, comments and corrections à la MSWord are a source of problem as often as a solution, so while I understand the reason people use them, I personally find inline corrections with comments markup (or a quick diff) more useful.
Matter of taste and work habits I suppose. There's something you can't argue against though: ressource usage. I typed entire sections of my last article on my Ben Nanonote.