I could see these becoming popular for datacenters, if server makers start including a hotswappable backplane for M.2 drives. Something similar to the SAS backplanes currently used. There would be much higher density than current 2.5in drives, and many workloads are heavily skewed towards reads.
The real differentiation, though, will be cost. There will need to be a significant cost advantage for these over buying "standard" SSDs, somewhere much closer to spinning rust prices.