There's little risk in dropping Kyro
There isn't anyone on the Android side able to beat ARM designed A72/A73/A75 cores by enough to matter. Sure, Apple is blowing away those ARM designed cores, but Android users aren't going to switch to iPhone over CPU performance, so that's irrelevant to Qualcomm.
Interesting choice to go with 48 cores. I guess they know they can't compete with Intel in single thread performance / IPC, so there's no point in clocking aggressively high and will instead try to make up for it with the number of cores. Sort of like AMD's strategy with Threadripper.
I'm sure the big cloud providers like Google and Amazon will give them a look, but they have such large scale these days they could afford to fund their own ARM design and create a complete SoC that does everything they need it to do and nothing they don't. So I wonder if there's really ever going to be a large enough market to justify Qualcomm designing an ARM server CPU.