re QM, GR and consistency
If A is inconsistent with B, and if A, then not-B. This is a theorem of logic, in the intended sense of logical consistency, under the usual interpretation of A and B as descriptive statements, and having the possible values "is true" or "is false". Interpretations of the propositional calculus with the values "is right" and "is wrong" would be novel and interesting, perhaps as a way of inferring values from facts.
Schrodinger's cat exemplified the problem - it's only relevant to QM.
re "when instruments take the measurements for science, human perception is no longer relevant within the Berkelian epistemology." Steve writes "And who reads the instrument? That's right, a human." One paper by the (very pro-physics) logical positivist philosopher Carnap has an appendix in which he speculates on science being done by machines - it dates from the 1950's (I don't have the reference to hand), and post-dates Schrodinger's cat. Your Room 101 would need to hold more than Anderson and Kurzweil.