Re: Desert Eagle? Are you kidding?
I'm not exactly sure what you're talking about. As previously mentioned, the DE is routinely chambered in .357 mag, .44 Mag, and (rarely) .50 AE. I own a Ruger Super Blackhawk (single action wild west revolver) in .44 Mag, and shoot it regularly (although after 18 rounds or so, I'm done with it for that visit). The gun is uncomfortable to shoot and the noise and kick are prodigious. On the other hand, it'll knock over a rather large steel plate at 25 yards where my 9mm will only go "tink".
Getting to the point: I rented a DE in .44 Mag one time, and was somewhat surprised at how much more comfortable it was to shoot than the Blackhawk, partly because of the increased mass and partly because of the gas operation. I wouldn't consider it to be something someone shoots "just once" and I don't see any real swaggering potential, to be perfectly honest. It's a massive gun, but that's because it shoots a high powered round.
.357 and .44 Mag are fairly common on the range in the US, and .357 Mag in particular is considered the "top stopper" for a defense round. .44 Mag is not generally considered a common defense round, being rather unmanageable in a tactical situation, but .44 Special (same slug, less powder) is.
...so I'm a little puzzled by this "desperately trying to compensate" thing. Unless one's experience with firearms was limited to the world of Ian Fleming, where .25 ACP is considered an effective defense round and .32 a top stopper.
Now, the .50 AE is a bit ridiculous. But the .50 AE is not considered a round for personal defense even in the movies.