Another way to disable autorun globally

For those who prefer registry settings (and those with Home versions that can't use GPedit.msc), set the

HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\Policies\Explorer\NoDriveTypeAutoRun

registry key to dword 0xFF.

However, Vista users may still be vulnerable to malware spread this way, see http://secunia.com/advisories/29458/