Media Center
I have looked several times at Pi as a media center and have discarded it every time. Sure, if you shell for the various extra licenses from the foundation Pi shop it can just about do HD media playback. None the less, media is and will remain its secondary function.
This board however, comes to M2M land from the other direction - from multimedia. I would expect it to do the job of "drop in replacement" for the 4 Debian based media center boxes I have around the house (a hodge-podge of ultra-small factor AMD E series and recycled thin clients). So if there will a half decent case for it, I will probably buy 3 of these without batting an eye lid. They will pay back compared to a PC (even a thin client) running MythTV/XbMC in 2-3 years time just from electricity power costs. Add to that the fanless/cool nature of the beast and the fact that it does not take any living room shelf space and it definitely starts to be quite appealing.