Fear & Loathing
Strangely it's the booze on top of the drugs which was probably the fatal blow. Remember the notorious E deaths where hidden in the details was the information that they'd drunk a bottle of vodka or similar ludicrous amounts. Drugs really screw most peoples judgement that's why having a less stoned buddy around is vital.
Preferably a buddy who is not a Samoan Attorney which is the traditional partner in Vegas if Hunter S. Thompson is to be believed:
The trunk of the car looked like a mobile police narcotics lab. We had two bags of grass, seventy five pellets of mescaline, five sheets of high powered blotter acid, a salt shaker half full of cocaine, and a whole galaxy of multicoloured uppers, downers, screamers, laughers and also a quart of tequila, a quart of rum, a case of Budweiser, a pint of raw ether and two dozen amyls.All this had been rounded up the night before, in a frenzy of high speed driving all over Los Angeles County from Topanga to Watts, we picked up everything we could get our hands on. Not that we needed all that for the trip, but once you get locked into a serious drug collection, the tendency is to push it as far as you can.