for that money
I'd rather pay a bit more and get better quality hardware from someone like HP. I just can't imagine deploying Supermicro grade stuff at a cost of $10s of thousands per node. give me good iLO(Supermicro's equivalent is OK but for the $ I want something better), Advanced ECC and other enterprise grade features (mainly higher reliability). Maybe throw in some advanced power management ala Dynamic power caps or something too.
Don't get me wrong I think supermicro stuff is OK -- my own personal server in a colo that hosts my email/websites/blog etc is Supermicro, I've used them off and on for many years. It's more about where in the value chain they fit, If' I'm going to pay $50-100k for a system, I want it to be higher grade than what SM offers. I don't care if the higher level software may handle fault tolerance, I'm willing to pay the cost to get more premium hardware underneath -- especially given the price delta would not be more than say 5-10%.
I really can't see myself paying more than $8-10k for a SM-based system. If the software is that valuable - it gets put on hardware that is at least somewhat more valuable (HP, or perhaps Dell - have not had much experience with IBM), with on site support etc.
Even more so if the solution is for a "branch office". May be less important if your deploying a grid of 100s of these systems in a data center. (but still I'd opt for the higher grade hardware).