While it is true we sighted humans can't observe radio or x-rays, we are able to observe things father along the spectrum (colors). If you are limited to a single wavelength, would you ever think to look for more?
If you are sure you are looking for a particle, would you ever build anything else but a particle sensor? If what you are looking for is really an interaction of fields that behaves like a particle under the conditions that such a particle is needed would you ever find it?
My point is that we are missing things that might be obvious because we are stuck with a limited why of looking at the universe. How do we break out of that? How many crack pot scientists have we dismissed who may have been headed in the right direction but unable to articulate it to the rest of us? Then ignored because of it.
What 5 or 11 dimensional events are we observing without knowing it? Do we already have 3 dimensional equations for those events and therefore building our understanding of the universe on accurate (for 3) but flawed (for 5) assumptions?
Am I now in the crack pot group?