Beta-blocker 'erases' unpleasant memories
Liam
hmmm #
Posted Monday 16th February 2009 16:24 GMT
"those who'd taken propranolol were simply less afraid than those who hadn't." less affraid doesnt equate to not affraid at all. and since there was obviously SOME fear from something it simply doesnt work! and giving people betablockers just makes them numb anyway.
thats like saying 'wow, heroine can stop people getting stressed out'
Marvin the Martian
Alcohol has been shown to do the same! #
Posted Monday 16th February 2009 16:24 GMT

(and it tastes far better and you can get it without prescription or 7.20quid NHS part-payment.)
That's what the eminently named prof DoraDuka has been saying for a while, anyways:
http://www.sussex.ac.uk/press_office/media/media698.shtml
Simon Cresswell
Do you reckon... #
Posted Monday 16th February 2009 16:24 GMT
.. I could get some to erase the memory of my Ex?
Anonymous Coward
Prescribed propanolol for anxiety... #
Posted Monday 16th February 2009 16:36 GMT

Obviously this is my subjective experience, but I was prescribed propanolol for anxiety (note: not hypertension) in my twenties. It seemed a little unconventional but previous treatment with SSRIs hadn't been terribly helpful. My experience was generally quite positive with minimal side effects. Obviously the paper reports a very specific set of circumstances where propanolol is given and a memory reactivated - but this seems quite a promising avenue to pursue.
Mike Crawshaw
How long #
Posted Monday 16th February 2009 16:36 GMT

before NuLab makes it mandatory to make us all less afraid of their latest crack-brained schemes?
richard
I lost three years... #
Posted Monday 16th February 2009 16:36 GMT
Prescribed Propranalol for regular migraines in my late teens and always put my hazy memories of my college years down to ingestion of... other substances.
Anonymous Coward
Useful information, but... #
Posted Monday 16th February 2009 19:05 GMT
The reaction to unpleasant situations is part of the learning experience; suppressing it could leave someone more vulnerable to the real world.
I take a similar beta blocker (bisoprolol) to control a cardiac arrhythmia, and have found that, for an hour or two after my daily dose, I am less bothered about unpaid bills and the like. This has sometimes led to problems.
This use of beta blockers may have some function in the treatment of people who are badly distressed by a very serious incident, but I hope it will not be used as a panacea, as too many drugs are.
Anonymous Coward
Could have it's uses. #
Posted Monday 16th February 2009 19:05 GMT

Would this help me when I forget to pay my tax bill - have less or no fear of being taken to jail :-)
Mines the one with the bottle of pills in the pocket.
Tawakalna
didn't do that for me... #
Posted Monday 16th February 2009 19:05 GMT
I was on this stuff for 3 years a while back and it didn't erase any unpleasant memories for me, if anything it made more because it gave me wild mood swings and monged me out. Not in a nice way either. Dreadful stuff. Bl**dy quacks.
Anonymous Coward
How long before... #
Posted Monday 16th February 2009 19:05 GMT

After every government cock up they put a dose in the water supply ?
Ah you say ! But then they would have to be dosing the water everyday !
Simpson
@Simon Cresswell #
Posted Monday 16th February 2009 19:05 GMT

".. I could get some to erase the memory of my Ex?"
But then you might date her again...
Robin Baker
I wonder? #
Posted Monday 16th February 2009 19:05 GMT
I was prescribed beta-blockers after a particularly stressful time in my life. Recently I have been asked to remember various things that happened around then (1996/7 ish) and have found it very difficult to do so. Perhaps this is the reason/excuse I need to explain why?
Anonymous Coward
Is it that... #
Posted Monday 16th February 2009 19:08 GMT

... the subjects were less afraid, or just didn't care?
Having been also prescribed propanolol as a migraine prophylactic I could testify to the latter...
evilbobthebob
It must be helpful #
Posted Monday 16th February 2009 19:08 GMT

It has lol in the name!
I'll get my coat.
Jim
Well... #
Posted Monday 16th February 2009 19:08 GMT
I'd love to lose most of highschool.
Anonymous Coward
I feel a great disturbance in the lulz... #
Posted Monday 16th February 2009 19:08 GMT

... It was as if millions of trolls suddenly cried out in anguish ... and were suddenly silenced.
It will spoil all the fun of trolling people into clicking on a link to goatse if there's now a way that they *can* un-see it after all!
Aaron
Re: Anonymous Coward: could the problem be your doctor? #
Posted Monday 16th February 2009 19:08 GMT
You cite being given SSRIs, and an extremely off-label prescription of an antihypertensive drug, for an anxiety problem. Were you ever prescribed an anxiolytic?
No, I don't think it's a good idea for anyone to be researching how to edit human memory. Who do *you* feel you can trust with that power? Why?
Anonymous Coward
Interesting #
Posted Monday 16th February 2009 19:08 GMT

I too was proscribed propanolol for anxiety and had very much the same experience as the other anonymous coward above...
yossarianuk
Need some for after work. #
Posted Monday 16th February 2009 19:08 GMT
I could do with some of this after every single day at work.
It might help to block the nightmares....
.
Nebulo
Erases unpleasant memories, eh? #
Posted Monday 16th February 2009 21:18 GMT

Hmmm. Sounds interesting.
So, roughly, how much do I need to take out about 30 years of watching my country being broken up, flogged off and the remains turned into a police state?
And don't tell Jacqui, or it'll be bloody Class A by the weekend.
David Eddleman
No #
Posted Monday 16th February 2009 21:19 GMT
"The reaction to unpleasant situations is part of the learning experience"
Err, so what you're trying to say is that people who were rape victims, or suffering from PTSD or from any myriad number of disorders should not be allowed to seek treatment from an event that by all accounts should not have happened to them?
kain preacher
Tech support wounder drug #
Posted Monday 16th February 2009 23:52 GMT
At least for management. Hand them out at will and you will forget why you want to leave the crappy company you work for .
Nick L
More years-old news #
Posted Monday 16th February 2009 23:52 GMT
Whilst it's always valuable to have research peer-reviewed, this is by no means the first discovery of this effect. Researchers at Harvard were studying it five years ago: http://www.hno.harvard.edu/gazette/2004/03.18/01-ptsd.html and in Montreal three years ago: http://www.chrcrm.org/main/modules/pageworks/index.php?page=002&id=1374
Anonymous Coward
drug to erase memory #
Posted Monday 16th February 2009 23:52 GMT
want blue smarties want blue smarties want blue smarties Now!!!
Alan Ferris
Off label ?! #
Posted Monday 16th February 2009 23:52 GMT
Not off label at all. The British National Formulary says quite clearly under Indications and dose:
"Anxiety with symptoms such as palpitation, sweating, tremor, 40 mg once daily, increased to 40 mg 3 times daily if necessary"
Section 4.1.2 on Anxiolytics says
"Beta-blockers (e.g. propranolol, oxprenolol) (section 2.4) do not affect psychological symptoms, such as worry, tension, and fear, but they do reduce autonomic symptoms, such as palpitation and tremor; they do not reduce non-autonomic symptoms, such as muscle tension. Beta-blockers are therefore indicated for patients with predominantly somatic symptoms; this, in turn, may prevent the onset of worry and fear. Patients with predominantly psychological symptoms may obtain no benefit."
It sounds like entirely appropriate prescribing to me... most other anxiolytics are of the same family as Valium
Anonymous Coward
@David Eddleman, re: learning experience. #
Posted Monday 16th February 2009 23:52 GMT
If you read my post all the way through, you would find I did not exclude any appropriate treatment for traumatised patients. I merely suggested that beta blockers should not be used as a panacea, as some drugs have been with unfortunate consequences,
As for the learning experience, it is, at all levels, the basis of our lives. Starting with our parents (or carers), siblings, then childhood friends, teachers, more friends, colleagues, strangers (friendly or otherwise), work, vehicles and other machinery, the media, world politics, whatever has shaped our view of the world.
For myself, I hate the idea of losing any of that, but I can also see that it may sometimes be necessary to help some who are distressed. I merely advised caution against yet another magic pill.
Pete "oranges" B.
OK... #
Posted Tuesday 17th February 2009 01:13 GMT

But let's say I /do/ want to see how far the rabbit hole goes, where's the red pill?
Mines the long, black one with the Micro Uzi's in the pockets.
David Wilkinson
Memory vs Conditioning ... #
Posted Tuesday 17th February 2009 01:13 GMT
No one is forgetting anything ... they are just breaking the subconscious association spider = electric shock.
After that the spider triggered discomfort which was enough to at least partially sustain the conditioning without the shocks.
This shows that taking a beta blocker will speed up desensitization. This could be very useful when someone is trying to overcome a traumatic event or a phobia.
I just miss the part where memory is affected?
Steve Roper
You can't do a goddamn double implant! #
Posted Tuesday 17th February 2009 05:08 GMT

He has really been there [to Mars]! Someone has erased his memory!
Use your head you dumb bitch! He's just acting out the secret-agent portion of his ego-trip!
I'm afraid that's not possible...
Why not?
BECAUSE WE HAVEN'T IMPLANTED IT YET!
(gives nod to Arnie :) )
David Kairns
Hello "Brave New World" #
Posted Tuesday 17th February 2009 05:08 GMT
Drugs, the "aware" way to live a life.
Soon: A drug to make you forget you're on drugs (also deals with pesky independent and creative thought).
James Halliday
From my very limited memory of a lecture a long time ago. #
Posted Tuesday 17th February 2009 09:29 GMT

I believe Beta blockers worked by 'relaxing' your heart (well stops it responding to stress and keeps it autonomic) , basically stops it racing - and therefore the nervous cascade a racing heart kicks off. You know the feeling, you get nervous, you feel your heart rate go up, you feel even worse, your heart rate goes up - basically panic.
Even when you've just had a shock and then you realize you're fine - you still have that little period where you don't feel right as you wait for your heart rate to go back down.
Anyway, response that was seen here, as has been pointed out, is f'in obvious. What would be more useful is if it carried on having an effect days, weeks, months later after the pill was taken. Or more interestingly if taking them whilst looking at the pictures and being shocked, caused the fear to be 'less imprinted' on the subject.
Anonymous Coward
Re: Well.../@Jim #
Posted Tuesday 17th February 2009 13:06 GMT
" I'd love to lose most of highschool. "
Are you, perchance, a teacher?
On another note -- why hasn't anyone mentioned Eternal Sunshine of the Spotless Mind?
Buy it, rent it, download it, whatever.
True must-see cinema.
Anonymous Coward
Re: Well.../@Jim #
Posted Tuesday 17th February 2009 13:06 GMT
Oops - just "spotted" the URL!
Vlad The Impugner
Imagine the possibilities.... #
Posted Tuesday 17th February 2009 13:06 GMT
......if you could autodose this on being rickrolled.
The fun would never end ldo
Anonymous Coward
@ Re: Well.../@Jim #
Posted Tuesday 17th February 2009 14:18 GMT

>"On another note -- why hasn't anyone mentioned Eternal Sunshine of the Spotless Mind?"
For some mysterious reason no-one can remember it...
Michael Dunn
@Mike Crawshaw #
Posted Wednesday 18th February 2009 19:01 GMT

They'll just put it in the water.
Water? Never touch the stuff!