Throttle account registration to prevent spam?
If spammers are using sweatshops to circumvent CAPTCHA, why not introduce a system that causes delays in setting up multiple webmail accounts e.g., from same IP address (space) effectively?
Another approach could be Google et al. to set up a limit against sending too many e-mails to too many recipients. A limit not even noticed by bona fide users could be detrimental for spammers sending large numbers of e-mails. Gmail could also throttle heavy outbound traffic that too many of the recipients report as spam. "Many mail recipients have reported your e-mails as spam, for the next X days you can only send Y e-mails per day, to max. Z recipients each..". A bit of cooperation between the mail providers would be helpful here, too.
Obviously, these measures would not stop spam entirely, but if the spamming process turns costly and complicated, it reduces the profitability = it works.


