Skeptics fail to learn the lessons of history
Having visited James Randi's site, and frequented a number of skeptics' forums, it seems to me that these people suffer from the same delusion that have dogged researchers since the time of ancient Greece: the idea that "learned men" know pretty much all there is to know about how the Universe works. The skeptics are very quick to dismiss any alternative worldview that doesn't fit in with their own materialistic perceptions. In their own way, this makes them as bigoted as any religionist; an atheist who claims "There is NO god" is actually making as positive a statement about god's existence as any religionist. The only accurate answer we can give to that question is "I don't know".
What riles me most about the skeptics' attitude is that they don't even want to allow research into the mere possibility of psychic phenomena. Granted, there are a lot of charlatans and shysters out there, but to simply deny even the possibility that psychic phenomena exist flies in the face of the most fundamental principles of science. Even if a lab has not yet turned up any empirical evidence of psychic phenomena, that doesn't mean that such phenomena don't or can't exist.
These are the same people who are willing to spend millions of dollars in the search for so-called "dark matter", which they can't prove exists and for which the only evidence is a half-baked theory concerning vorticity in spiral galaxies. Yet they instantly ridicule any efforts to investigate potential powers of the human mind. For this reason, I prefer agnosticism, and could no more become a "skeptic" than I could become a Christian or a Muslim.
All I can say to the skeptics is: "You don't have enough information about the Universe to make that judgement."